STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MACROH2A1Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (371 aa)    
Predicted Functional Partners:
MYSM1
Myb like, SWIRM and MPN domains 1.
   
 0.984
SPOP
Speckle type BTB/POZ protein.
    
 
 0.874
PARP1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
    
 
 0.868
KDM6A
Lysine demethylase 6A.
  
 0.866
LOC108297774
Uncharacterized protein.
  
 0.861
KDM6B
Lysine demethylase 6B.
  
 0.861
HDAC11
Histone deacetylase 11.
    
 0.860
GLYR1
Glyoxylate reductase 1 homolog.
    
 
 0.844
HDAC2
Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    
 0.831
AIFM1
Apoptosis inducing factor mitochondria associated 1.
   
 0.823
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.