Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CRYABCrystallin alpha B; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (175 aa)    
Predicted Functional Partners:
CRYAA
SHSP domain-containing protein; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
    
 0.974
HSPB2
SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.
   
 
 0.946
ENSCCAP00000019729
SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.
   
 0.934
HSPB1
SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.
   
 0.934
BAG3
BCL2 associated athanogene 3.
   
 0.924
CRYBB2
Crystallin beta B2; Belongs to the beta/gamma-crystallin family.
   
 
 0.912
SNCA
Alpha-synuclein; Belongs to the synuclein family.
    
 
 0.907
CRYBA1
Crystallin beta A1; Belongs to the beta/gamma-crystallin family.
   
 
 0.899
APP
Amyloid beta precursor protein.
   
 
 0.896
HSPB6
Heat shock protein family B (small) member 6; Belongs to the small heat shock protein (HSP20) family.
   
 0.891
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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