| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APAF1 | BAK1 | ENSCCAP00000036428 | ENSCCAP00000040261 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | BCL2 antagonist/killer 1. | 0.727 |
| APAF1 | BAX | ENSCCAP00000036428 | ENSCCAP00000011956 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | BCL2 associated X, apoptosis regulator. | 0.765 |
| APAF1 | BCL2 | ENSCCAP00000036428 | ENSCCAP00000005426 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | BCL2 apoptosis regulator. | 0.849 |
| APAF1 | BCL2L1 | ENSCCAP00000036428 | ENSCCAP00000011593 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | BCL2 like 1. | 0.832 |
| APAF1 | CASP3 | ENSCCAP00000036428 | ENSCCAP00000028701 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Caspase 3; Belongs to the peptidase C14A family. | 0.981 |
| APAF1 | CASP9 | ENSCCAP00000036428 | ENSCCAP00000005136 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Caspase 9; Belongs to the peptidase C14A family. | 0.999 |
| APAF1 | CYC1 | ENSCCAP00000036428 | ENSCCAP00000029760 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Cytochrome c1. | 0.507 |
| APAF1 | ENSCCAP00000009063 | ENSCCAP00000036428 | ENSCCAP00000009063 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Uncharacterized protein; Belongs to the peptidase C14A family. | 0.981 |
| APAF1 | LOC108304381 | ENSCCAP00000036428 | ENSCCAP00000001557 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.996 |
| BAK1 | APAF1 | ENSCCAP00000040261 | ENSCCAP00000036428 | BCL2 antagonist/killer 1. | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | 0.727 |
| BAK1 | BAX | ENSCCAP00000040261 | ENSCCAP00000011956 | BCL2 antagonist/killer 1. | BCL2 associated X, apoptosis regulator. | 0.955 |
| BAK1 | BCL2 | ENSCCAP00000040261 | ENSCCAP00000005426 | BCL2 antagonist/killer 1. | BCL2 apoptosis regulator. | 0.977 |
| BAK1 | BCL2L1 | ENSCCAP00000040261 | ENSCCAP00000011593 | BCL2 antagonist/killer 1. | BCL2 like 1. | 0.996 |
| BAK1 | CASP9 | ENSCCAP00000040261 | ENSCCAP00000005136 | BCL2 antagonist/killer 1. | Caspase 9; Belongs to the peptidase C14A family. | 0.457 |
| BAK1 | LOC108304381 | ENSCCAP00000040261 | ENSCCAP00000001557 | BCL2 antagonist/killer 1. | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.905 |
| BAX | APAF1 | ENSCCAP00000011956 | ENSCCAP00000036428 | BCL2 associated X, apoptosis regulator. | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | 0.765 |
| BAX | BAK1 | ENSCCAP00000011956 | ENSCCAP00000040261 | BCL2 associated X, apoptosis regulator. | BCL2 antagonist/killer 1. | 0.955 |
| BAX | BCL2 | ENSCCAP00000011956 | ENSCCAP00000005426 | BCL2 associated X, apoptosis regulator. | BCL2 apoptosis regulator. | 0.966 |
| BAX | BCL2L1 | ENSCCAP00000011956 | ENSCCAP00000011593 | BCL2 associated X, apoptosis regulator. | BCL2 like 1. | 0.961 |
| BAX | CASP3 | ENSCCAP00000011956 | ENSCCAP00000028701 | BCL2 associated X, apoptosis regulator. | Caspase 3; Belongs to the peptidase C14A family. | 0.449 |