STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL21Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)    
Predicted Functional Partners:
IL21R
Interleukin 21 receptor.
  
 0.997
IL2RG
Fibronectin type-III domain-containing protein.
   
 0.976
JAK1
Tyrosine-protein kinase.
   
 
 0.960
JAK3
Tyrosine-protein kinase.
   
 
 0.918
STAT3
Signal transducer and activator of transcription.
   
 
 0.854
IL23R
Interleukin 23 receptor.
   
 
 0.821
IFNAR1
Interferon alpha and beta receptor subunit 1.
  
  
 0.819
IL22RA1
Interleukin 22 receptor subunit alpha 1.
  
  
 0.818
IL2RA
Interleukin 2 receptor subunit alpha.
   
 
 0.814
CD40LG
CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
  
  
 0.800
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.