DRAXIN protein (Cebus capucinus) - STRING interaction network

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DRAXIN

Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (350 aa)

Predicted Functional Partners:

NTN1

0.900

DCC

0.889

NEO1

0.863

NTN3

0.807

IGDCC4

0.770

NTN5

0.719

SPICE1

0.691

IGDCC3

0.688

NTNG1

0.638

FNDC1

0.583

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCC	DRAXIN	ENSCCAP00000002014	ENSCCAP00000003530	DCC netrin 1 receptor.	Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.	0.889
DCC	NTN1	ENSCCAP00000002014	ENSCCAP00000025768	DCC netrin 1 receptor.	Netrin 1.	0.994
DCC	NTN3	ENSCCAP00000002014	ENSCCAP00000002744	DCC netrin 1 receptor.	Netrin 3.	0.943
DCC	NTN5	ENSCCAP00000002014	ENSCCAP00000029456	DCC netrin 1 receptor.	Netrin 5.	0.881
DCC	NTNG1	ENSCCAP00000002014	ENSCCAP00000024490	DCC netrin 1 receptor.	Netrin G1.	0.775
DRAXIN	DCC	ENSCCAP00000003530	ENSCCAP00000002014	Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.	DCC netrin 1 receptor.	0.889
DRAXIN	FNDC1	ENSCCAP00000003530	ENSCCAP00000008475	Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.	Fibronectin type III domain containing 1.	0.583
DRAXIN	IGDCC3	ENSCCAP00000003530	ENSCCAP00000022633	Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.	Immunoglobulin superfamily DCC subclass member 3.	0.688
DRAXIN	IGDCC4	ENSCCAP00000003530	ENSCCAP00000032073	Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.	Immunoglobulin superfamily DCC subclass member 4.	0.770
DRAXIN	NEO1	ENSCCAP00000003530	ENSCCAP00000022255	Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.	Neogenin 1.	0.863
DRAXIN	NTN1	ENSCCAP00000003530	ENSCCAP00000025768	Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.	Netrin 1.	0.900
DRAXIN	NTN3	ENSCCAP00000003530	ENSCCAP00000002744	Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.	Netrin 3.	0.807
DRAXIN	NTN5	ENSCCAP00000003530	ENSCCAP00000029456	Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.	Netrin 5.	0.719
DRAXIN	NTNG1	ENSCCAP00000003530	ENSCCAP00000024490	Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.	Netrin G1.	0.638
DRAXIN	SPICE1	ENSCCAP00000003530	ENSCCAP00000017456	Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.	Uncharacterized protein.	0.691
FNDC1	DRAXIN	ENSCCAP00000008475	ENSCCAP00000003530	Fibronectin type III domain containing 1.	Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.	0.583
FNDC1	NTN1	ENSCCAP00000008475	ENSCCAP00000025768	Fibronectin type III domain containing 1.	Netrin 1.	0.677
FNDC1	NTN3	ENSCCAP00000008475	ENSCCAP00000002744	Fibronectin type III domain containing 1.	Netrin 3.	0.677
FNDC1	NTN5	ENSCCAP00000008475	ENSCCAP00000029456	Fibronectin type III domain containing 1.	Netrin 5.	0.677
FNDC1	NTNG1	ENSCCAP00000008475	ENSCCAP00000024490	Fibronectin type III domain containing 1.	Netrin G1.	0.704

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