Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACE2Angiotensin-converting enzyme. (801 aa)    
Predicted Functional Partners:
AGT
Angiotensinogen; Belongs to the serpin family.
    
 0.987
DPP4
Dipeptidyl peptidase 4; Belongs to the peptidase S9B family.
   
 
 0.965
REN
Renin; Belongs to the peptidase A1 family.
     
 0.960
SLC6A19
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
   
 
 0.951
TMPRSS2
Transmembrane serine protease 2; Belongs to the peptidase S1 family.
    
 0.944
MME
Membrane metalloendopeptidase.
  
  
 0.938
KNG1
Kininogen 1.
    
 0.934
ACE
Angiotensin-converting enzyme.
  
 
0.928
AGTR1
Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.923
CMA1
Chymase 1; Belongs to the peptidase S1 family.
    
 0.918
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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