FASLG protein (Cebus capucinus) - STRING interaction network

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Score

FASLG

Fas ligand; Belongs to the tumor necrosis factor family. (281 aa)

Predicted Functional Partners:

FAS

0.995

FADD

0.962

LUM

0.960

CASP8

0.958

FOXO4

0.951

CASP10

0.873

CD40LG

0.870

PRF1

0.856

FAU

0.829

LOC108288201

0.829

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASP10	CASP8	ENSCCAP00000013358	ENSCCAP00000021133	Caspase 10; Belongs to the peptidase C14A family.	Caspase 8; Belongs to the peptidase C14A family.	0.993
CASP10	FADD	ENSCCAP00000013358	ENSCCAP00000003237	Caspase 10; Belongs to the peptidase C14A family.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.994
CASP10	FAS	ENSCCAP00000013358	ENSCCAP00000018243	Caspase 10; Belongs to the peptidase C14A family.	Fas cell surface death receptor.	0.967
CASP10	FASLG	ENSCCAP00000013358	ENSCCAP00000037308	Caspase 10; Belongs to the peptidase C14A family.	Fas ligand; Belongs to the tumor necrosis factor family.	0.873
CASP8	CASP10	ENSCCAP00000021133	ENSCCAP00000013358	Caspase 8; Belongs to the peptidase C14A family.	Caspase 10; Belongs to the peptidase C14A family.	0.993
CASP8	FADD	ENSCCAP00000021133	ENSCCAP00000003237	Caspase 8; Belongs to the peptidase C14A family.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.998
CASP8	FAS	ENSCCAP00000021133	ENSCCAP00000018243	Caspase 8; Belongs to the peptidase C14A family.	Fas cell surface death receptor.	0.980
CASP8	FASLG	ENSCCAP00000021133	ENSCCAP00000037308	Caspase 8; Belongs to the peptidase C14A family.	Fas ligand; Belongs to the tumor necrosis factor family.	0.958
CD40LG	FAS	ENSCCAP00000009246	ENSCCAP00000018243	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Fas cell surface death receptor.	0.839
CD40LG	FASLG	ENSCCAP00000009246	ENSCCAP00000037308	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Fas ligand; Belongs to the tumor necrosis factor family.	0.870
FADD	CASP10	ENSCCAP00000003237	ENSCCAP00000013358	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Caspase 10; Belongs to the peptidase C14A family.	0.994
FADD	CASP8	ENSCCAP00000003237	ENSCCAP00000021133	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Caspase 8; Belongs to the peptidase C14A family.	0.998
FADD	FAS	ENSCCAP00000003237	ENSCCAP00000018243	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Fas cell surface death receptor.	0.998
FADD	FASLG	ENSCCAP00000003237	ENSCCAP00000037308	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Fas ligand; Belongs to the tumor necrosis factor family.	0.962
FAS	CASP10	ENSCCAP00000018243	ENSCCAP00000013358	Fas cell surface death receptor.	Caspase 10; Belongs to the peptidase C14A family.	0.967
FAS	CASP8	ENSCCAP00000018243	ENSCCAP00000021133	Fas cell surface death receptor.	Caspase 8; Belongs to the peptidase C14A family.	0.980
FAS	CD40LG	ENSCCAP00000018243	ENSCCAP00000009246	Fas cell surface death receptor.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.839
FAS	FADD	ENSCCAP00000018243	ENSCCAP00000003237	Fas cell surface death receptor.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.998
FAS	FASLG	ENSCCAP00000018243	ENSCCAP00000037308	Fas cell surface death receptor.	Fas ligand; Belongs to the tumor necrosis factor family.	0.995
FASLG	CASP10	ENSCCAP00000037308	ENSCCAP00000013358	Fas ligand; Belongs to the tumor necrosis factor family.	Caspase 10; Belongs to the peptidase C14A family.	0.873