node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCDC24 | MED16 | ENSCCAP00000023096 | ENSCCAP00000010110 | Coiled-coil domain containing 24. | Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.660 |
CCDC24 | TUT4 | ENSCCAP00000023096 | ENSCCAP00000038143 | Coiled-coil domain containing 24. | Terminal uridylyl transferase 4. | 0.670 |
CCDC24 | ZNF644 | ENSCCAP00000023096 | ENSCCAP00000021829 | Coiled-coil domain containing 24. | Zinc finger protein 644. | 0.685 |
DIS3L2 | EPRS1 | ENSCCAP00000036354 | ENSCCAP00000020931 | DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] | Glutamyl-prolyl-tRNA synthetase. | 0.512 |
DIS3L2 | TUT4 | ENSCCAP00000036354 | ENSCCAP00000038143 | DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] | Terminal uridylyl transferase 4. | 0.585 |
ENSCCAP00000001719 | TUT4 | ENSCCAP00000001719 | ENSCCAP00000038143 | CCHC-type domain-containing protein. | Terminal uridylyl transferase 4. | 0.491 |
EPRS1 | DIS3L2 | ENSCCAP00000020931 | ENSCCAP00000036354 | Glutamyl-prolyl-tRNA synthetase. | DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] | 0.512 |
EPRS1 | TUT4 | ENSCCAP00000020931 | ENSCCAP00000038143 | Glutamyl-prolyl-tRNA synthetase. | Terminal uridylyl transferase 4. | 0.592 |
LIN28A | TUT4 | ENSCCAP00000002079 | ENSCCAP00000038143 | CCHC-type domain-containing protein. | Terminal uridylyl transferase 4. | 0.491 |
LIN28B | TUT4 | ENSCCAP00000006310 | ENSCCAP00000038143 | Lin-28 homolog B. | Terminal uridylyl transferase 4. | 0.582 |
MARF1 | TUT4 | ENSCCAP00000038781 | ENSCCAP00000038143 | Meiosis regulator and mRNA stability factor 1. | Terminal uridylyl transferase 4. | 0.534 |
MED16 | CCDC24 | ENSCCAP00000010110 | ENSCCAP00000023096 | Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Coiled-coil domain containing 24. | 0.660 |
MED16 | TUT4 | ENSCCAP00000010110 | ENSCCAP00000038143 | Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Terminal uridylyl transferase 4. | 0.601 |
MED16 | ZNF644 | ENSCCAP00000010110 | ENSCCAP00000021829 | Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Zinc finger protein 644. | 0.652 |
PAPOLG | TUT4 | ENSCCAP00000018424 | ENSCCAP00000038143 | Poly(A) polymerase gamma. | Terminal uridylyl transferase 4. | 0.534 |
TUT4 | CCDC24 | ENSCCAP00000038143 | ENSCCAP00000023096 | Terminal uridylyl transferase 4. | Coiled-coil domain containing 24. | 0.670 |
TUT4 | DIS3L2 | ENSCCAP00000038143 | ENSCCAP00000036354 | Terminal uridylyl transferase 4. | DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] | 0.585 |
TUT4 | ENSCCAP00000001719 | ENSCCAP00000038143 | ENSCCAP00000001719 | Terminal uridylyl transferase 4. | CCHC-type domain-containing protein. | 0.491 |
TUT4 | EPRS1 | ENSCCAP00000038143 | ENSCCAP00000020931 | Terminal uridylyl transferase 4. | Glutamyl-prolyl-tRNA synthetase. | 0.592 |
TUT4 | LIN28A | ENSCCAP00000038143 | ENSCCAP00000002079 | Terminal uridylyl transferase 4. | CCHC-type domain-containing protein. | 0.491 |