STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFS35546.1Hypothetical protein. (297 aa)    
Predicted Functional Partners:
SFS92779.1
Protein of unknown function.
  
     0.739
arc
Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
  
    0.719
SFS35529.1
Cell division protein FtsI/penicillin-binding protein 2.
 
     0.694
ispG
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
  
    0.666
SFS37531.1
Cobalamin-independent synthase, Catalytic domain.
  
     0.664
SFS67103.1
Protein of unknown function.
  
     0.567
SFS50720.1
Lsr2 protein.
  
     0.547
SFS54014.1
Regulator of protease activity HflC, stomatin/prohibitin superfamily.
  
    0.536
SFS80324.1
SPFH domain, Band 7 family protein.
  
    0.536
SFS57093.1
Lsr2 protein.
  
     0.533
Your Current Organism:
Saccharopolyspora flava
NCBI taxonomy Id: 95161
Other names: DSM 44771, IFO 16345, JCM 10665, NBRC 16345, S. flava, Saccharopolyspora flava Lu et al. 2001, strain 07
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.