STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFS36152.1Ammonium transporter. (446 aa)    
Predicted Functional Partners:
SFS36141.1
Nitrogen regulatory protein P-II family; Belongs to the P(II) protein family.
 0.999
SFS33070.1
Glutamate synthase (NADH) large subunit.
 
  
 0.936
SFT05429.1
Glutamate synthase (NADH) large subunit.
 
  
 0.936
SFS68141.1
Glutamine synthetase.
  
  
 0.796
SFS92209.1
Glutamine synthetase.
  
  
 0.666
SFS64317.1
Glutamine synthetase.
  
  
 0.655
SFS80036.1
Aconitase.
  
 
 0.600
SFT05037.1
L-glutamine synthetase.
  
  
 0.588
SFS30842.1
Urease subunit gamma/beta.
  
  
 0.580
glnE
Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]
     
 0.516
Your Current Organism:
Saccharopolyspora flava
NCBI taxonomy Id: 95161
Other names: DSM 44771, IFO 16345, JCM 10665, NBRC 16345, S. flava, Saccharopolyspora flava Lu et al. 2001, strain 07
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