node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFS43685.1 | SFS46914.1 | SAMN05660874_01106 | SAMN05660874_01354 | Chaperone protein HscA; Belongs to the heat shock protein 70 family. | Hypothetical protein. | 0.914 |
SFS43685.1 | SFS85996.1 | SAMN05660874_01106 | SAMN05660874_03801 | Chaperone protein HscA; Belongs to the heat shock protein 70 family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.979 |
SFS43685.1 | SFS94538.1 | SAMN05660874_01106 | SAMN05660874_04461 | Chaperone protein HscA; Belongs to the heat shock protein 70 family. | Hypothetical protein. | 0.914 |
SFS43685.1 | SFS95862.1 | SAMN05660874_01106 | SAMN05660874_04523 | Chaperone protein HscA; Belongs to the heat shock protein 70 family. | DnaJ domain-containing protein. | 0.977 |
SFS43685.1 | dnaJ | SAMN05660874_01106 | SAMN05660874_03851 | Chaperone protein HscA; Belongs to the heat shock protein 70 family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.968 |
SFS43685.1 | dnaJ-2 | SAMN05660874_01106 | SAMN05660874_04325 | Chaperone protein HscA; Belongs to the heat shock protein 70 family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.972 |
SFS43685.1 | groL | SAMN05660874_01106 | SAMN05660874_01056 | Chaperone protein HscA; Belongs to the heat shock protein 70 family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.914 |
SFS43685.1 | groL-2 | SAMN05660874_01106 | SAMN05660874_01965 | Chaperone protein HscA; Belongs to the heat shock protein 70 family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.911 |
SFS43685.1 | grpE | SAMN05660874_01106 | SAMN05660874_03850 | Chaperone protein HscA; Belongs to the heat shock protein 70 family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.972 |
SFS43685.1 | rplP | SAMN05660874_01106 | SAMN05660874_01150 | Chaperone protein HscA; Belongs to the heat shock protein 70 family. | Large subunit ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | 0.909 |
SFS46914.1 | SFS43685.1 | SAMN05660874_01354 | SAMN05660874_01106 | Hypothetical protein. | Chaperone protein HscA; Belongs to the heat shock protein 70 family. | 0.914 |
SFS46914.1 | SFS85996.1 | SAMN05660874_01354 | SAMN05660874_03801 | Hypothetical protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.816 |
SFS46914.1 | groL | SAMN05660874_01354 | SAMN05660874_01056 | Hypothetical protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.670 |
SFS46914.1 | groL-2 | SAMN05660874_01354 | SAMN05660874_01965 | Hypothetical protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.670 |
SFS46914.1 | grpE | SAMN05660874_01354 | SAMN05660874_03850 | Hypothetical protein. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.816 |
SFS46914.1 | rplP | SAMN05660874_01354 | SAMN05660874_01150 | Hypothetical protein. | Large subunit ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | 0.724 |
SFS85996.1 | SFS43685.1 | SAMN05660874_03801 | SAMN05660874_01106 | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | Chaperone protein HscA; Belongs to the heat shock protein 70 family. | 0.979 |
SFS85996.1 | SFS46914.1 | SAMN05660874_03801 | SAMN05660874_01354 | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | Hypothetical protein. | 0.816 |
SFS85996.1 | SFS94538.1 | SAMN05660874_03801 | SAMN05660874_04461 | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | Hypothetical protein. | 0.816 |
SFS85996.1 | SFS95862.1 | SAMN05660874_03801 | SAMN05660874_04523 | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | DnaJ domain-containing protein. | 0.911 |