STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFS51723.1Biotin transport system substrate-specific component. (192 aa)    
Predicted Functional Partners:
SFS51757.1
Biotin transport system ATP-binding protein.
 
 
 0.999
SFS51773.1
Biotin transport system permease protein.
 
 0.999
SFT01487.1
Cobalt/nickel transport system ATP-binding protein.
   
 0.973
SFT01476.1
Cobalt/nickel transport system permease protein.
  
 0.943
SFS51738.1
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II.
 
    0.896
SFS51744.1
acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
 
    0.818
cobB
Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
  
 0.640
SFS40854.1
BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase.
 
   
 0.565
SFS51710.1
ATP-dependent DNA helicase DinG.
       0.542
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
  
 0.531
Your Current Organism:
Saccharopolyspora flava
NCBI taxonomy Id: 95161
Other names: DSM 44771, IFO 16345, JCM 10665, NBRC 16345, S. flava, Saccharopolyspora flava Lu et al. 2001, strain 07
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.