STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFS53254.1NAD+ diphosphatase. (308 aa)    
Predicted Functional Partners:
SFS51690.1
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
    
 0.856
SFS80123.1
NAD-dependent deacetylase.
    
 0.841
nadE
NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.835
SFS30954.1
5'-nucleotidase; Belongs to the 5'-nucleotidase family.
    
  0.832
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
     
 0.829
SFS53267.1
Predicted Zn-dependent peptidase.
  
    0.825
SFS53278.1
Predicted Zn-dependent peptidase.
  
    0.824
SFS33514.1
Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Belongs to the NadC/ModD family.
     
 0.821
SFS34133.1
Competence/damage-inducible protein cinA; Belongs to the CinA family.
     
 0.820
nadK
NAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.820
Your Current Organism:
Saccharopolyspora flava
NCBI taxonomy Id: 95161
Other names: DSM 44771, IFO 16345, JCM 10665, NBRC 16345, S. flava, Saccharopolyspora flava Lu et al. 2001, strain 07
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.