node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFS36781.1 | SFS39741.1 | SAMN05660874_00572 | SAMN05660874_00799 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 2-oxoglutarate dehydrogenase E1 component. | 0.616 |
SFS36781.1 | SFS43396.1 | SAMN05660874_00572 | SAMN05660874_01084 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Malate synthase; Belongs to the malate synthase family. | 0.870 |
SFS36781.1 | SFS56193.1 | SAMN05660874_00572 | SAMN05660874_01905 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Citrate synthase; Belongs to the citrate synthase family. | 0.918 |
SFS36781.1 | SFS65935.1 | SAMN05660874_00572 | SAMN05660874_02392 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Acetyl/propionyl-CoA carboxylase, alpha subunit. | 0.941 |
SFS36781.1 | SFS67290.1 | SAMN05660874_00572 | SAMN05660874_02555 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.901 |
SFS36781.1 | SFS75234.1 | SAMN05660874_00572 | SAMN05660874_03145 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | acetyl-CoA synthetase. | 0.833 |
SFS36781.1 | SFS80036.1 | SAMN05660874_00572 | SAMN05660874_03390 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Aconitase. | 0.581 |
SFS36781.1 | fumC | SAMN05660874_00572 | SAMN05660874_01700 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Fumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.788 |
SFS36781.1 | mdh | SAMN05660874_00572 | SAMN05660874_03472 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.924 |
SFS36781.1 | sucC | SAMN05660874_00572 | SAMN05660874_01010 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.704 |
SFS39741.1 | SFS36781.1 | SAMN05660874_00799 | SAMN05660874_00572 | 2-oxoglutarate dehydrogenase E1 component. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.616 |
SFS39741.1 | SFS43396.1 | SAMN05660874_00799 | SAMN05660874_01084 | 2-oxoglutarate dehydrogenase E1 component. | Malate synthase; Belongs to the malate synthase family. | 0.538 |
SFS39741.1 | SFS56193.1 | SAMN05660874_00799 | SAMN05660874_01905 | 2-oxoglutarate dehydrogenase E1 component. | Citrate synthase; Belongs to the citrate synthase family. | 0.980 |
SFS39741.1 | SFS65935.1 | SAMN05660874_00799 | SAMN05660874_02392 | 2-oxoglutarate dehydrogenase E1 component. | Acetyl/propionyl-CoA carboxylase, alpha subunit. | 0.997 |
SFS39741.1 | SFS67290.1 | SAMN05660874_00799 | SAMN05660874_02555 | 2-oxoglutarate dehydrogenase E1 component. | Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.931 |
SFS39741.1 | SFS75234.1 | SAMN05660874_00799 | SAMN05660874_03145 | 2-oxoglutarate dehydrogenase E1 component. | acetyl-CoA synthetase. | 0.511 |
SFS39741.1 | SFS80036.1 | SAMN05660874_00799 | SAMN05660874_03390 | 2-oxoglutarate dehydrogenase E1 component. | Aconitase. | 0.873 |
SFS39741.1 | fumC | SAMN05660874_00799 | SAMN05660874_01700 | 2-oxoglutarate dehydrogenase E1 component. | Fumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.940 |
SFS39741.1 | mdh | SAMN05660874_00799 | SAMN05660874_03472 | 2-oxoglutarate dehydrogenase E1 component. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.927 |
SFS39741.1 | sucC | SAMN05660874_00799 | SAMN05660874_01010 | 2-oxoglutarate dehydrogenase E1 component. | succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.995 |