STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFS92787.1Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (924 aa)    
Predicted Functional Partners:
SFS68070.1
2-oxoglutarate dehydrogenase E2 component.
 
 0.966
SFS85667.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
 
 0.944
SFS65935.1
Acetyl/propionyl-CoA carboxylase, alpha subunit.
  
 0.937
SFS89934.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
 
 0.934
SFS32541.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.933
SFS39741.1
2-oxoglutarate dehydrogenase E1 component.
 
 0.929
SFS32568.1
Dihydrolipoamide dehydrogenase.
  
 
 0.858
SFS68064.1
Dihydrolipoamide dehydrogenase.
  
 
 0.858
SFT09165.1
Hypothetical protein.
  
 0.842
SFT01083.1
2-oxoisovalerate dehydrogenase E1 component.
    
 0.834
Your Current Organism:
Saccharopolyspora flava
NCBI taxonomy Id: 95161
Other names: DSM 44771, IFO 16345, JCM 10665, NBRC 16345, S. flava, Saccharopolyspora flava Lu et al. 2001, strain 07
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