STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDV00801.1Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1236 aa)    
Predicted Functional Partners:
metF
5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family.
 
 
 0.998
metE
Methionine synthase (B12-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.954
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
  
 
 0.948
SDV08268.1
Cystathionine gamma-lyase.
  
 
 0.948
SDV14292.1
Sulfite reductase (NADPH) flavoprotein alpha-component.
  
 0.941
metXS
Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
  
 
 0.938
SDV13883.1
Homoserine dehydrogenase.
  
 
 0.935
gcvT
Aminomethyltransferase.
  
 
 0.928
gcvT-2
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.
  
 
 0.928
SDU90021.1
Aspartate kinase; Belongs to the aspartokinase family.
  
 
 0.885
Your Current Organism:
Pseudomonas vancouverensis
NCBI taxonomy Id: 95300
Other names: ATCC 700688, CCUG 49675, CIP 106707, P. vancouverensis, strain DhA-51
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