STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDV02699.1DNA-O6-methylguanine--protein-cysteine S-methyltransferase /Transcriptional regulator Ada. (354 aa)    
Predicted Functional Partners:
SDV13589.1
DNA-3-methyladenine glycosylase II.
 
 
 0.927
rpoS
RNA polymerase, sigma 38 subunit, RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.
   
   0.921
rpoH
RNA polymerase, sigma 32 subunit, RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
   
   0.921
rpoD
RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
   0.921
alkB
DNA-N1-methyladenine dioxygenase.
 
  
 0.857
SDV06035.1
DNA-3-methyladenine glycosylase II.
  
 
 0.853
SDV06028.1
DNA-O6-methylguanine--protein-cysteine S-methyltransferase /Transcriptional regulator Ada; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. Belongs to the MGMT family.
 
  
0.809
SDV02715.1
Hypothetical protein.
 
     0.770
SDV11404.1
Regulatory inactivation of DnaA Hda protein; Belongs to the DnaA family. HdA subfamily.
    
   0.605
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
    
   0.605
Your Current Organism:
Pseudomonas vancouverensis
NCBI taxonomy Id: 95300
Other names: ATCC 700688, CCUG 49675, CIP 106707, P. vancouverensis, strain DhA-51
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