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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DNAJC5DnaJ heat shock protein family (Hsp40) member C5. (198 aa)    
Predicted Functional Partners:
RIMS2
Regulating synaptic membrane exocytosis 2.
     
 0.941
TFIP11
Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...]
    
 
 0.876
CDC5L
Cell division cycle 5 like.
   
 
 0.867
CRNKL1
Crooked neck pre-mRNA splicing factor 1.
    
 
 0.838
PLRG1
Pleiotropic regulator 1.
    
 
 0.833
PRPF19
Pre-mRNA processing factor 19.
    
   0.832
BUD31
BUD31 homolog.
    
   0.832
HSPA14
Heat shock protein family A (Hsp70) member 14; Belongs to the heat shock protein 70 family.
  
 0.829
EFTUD2
Elongation factor Tu GTP binding domain containing 2.
  
 0.817
PRPF8
Pre-mRNA processing factor 8.
    
 
 0.806
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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