STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KREMEN2Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (462 aa)    
Predicted Functional Partners:
FANCM
FA complementation group M.
   
 0.995
DKK1
Dickkopf WNT signaling pathway inhibitor 1.
    
 0.922
CENPT
Centromere protein T.
   
 0.880
CENPX
Centromere protein X.
    
 0.880
CENPW
Centromere protein W.
   
 0.878
ERCC4
ERCC excision repair 4, endonuclease catalytic subunit.
   
 0.752
FAAP24
FA core complex associated protein 24.
    
 0.729
MUS81
MUS81 structure-specific endonuclease subunit.
   
 0.724
CENPM
Centromere protein M.
   
 0.722
CENPQ
Centromere protein Q.
   
 0.721
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.