Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HPGD15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa)    
Predicted Functional Partners:
LOC105599873
PKS_ER domain-containing protein.
   
 
 0.941
PTGES
Prostaglandin E synthase.
     
 0.940
PTGR2
Uncharacterized protein.
   
 
 0.940
PTGES2
Prostaglandin E synthase 2.
     
 0.927
ZADH2
Zinc binding alcohol dehydrogenase domain containing 2.
   
  0.923
PRXL2B
Peroxiredoxin like 2B.
     
 0.915
CBR3
Carbonyl reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.908
FITM1
Fat storage inducing transmembrane protein 1.
      
 0.678
FABP3
Fatty acid binding protein 3; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
     
 0.598
ERLIN2
ER lipid raft associated 2.
      
 0.573
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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