ETV1 protein (Cercocebus atys) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

ETV1

ETS variant 1. (491 aa)

Predicted Functional Partners:

COP1

0.906

STK40

0.900

DET1

0.819

ETV5

0.684

EP300

0.652

TMPRSS2

0.620

TP53

0.593

EWSR1

0.583

KCNN2

0.569

KCNN3

0.569

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COP1	DET1	ENSCATP00000006359	ENSCATP00000034514	COP1 E3 ubiquitin ligase.	Uncharacterized protein.	0.987
COP1	ETV1	ENSCATP00000006359	ENSCATP00000001005	COP1 E3 ubiquitin ligase.	ETS variant 1.	0.906
COP1	ETV5	ENSCATP00000006359	ENSCATP00000038587	COP1 E3 ubiquitin ligase.	ETS variant 5.	0.905
COP1	STK40	ENSCATP00000006359	ENSCATP00000032869	COP1 E3 ubiquitin ligase.	Serine/threonine kinase 40.	0.900
COP1	TP53	ENSCATP00000006359	ENSCATP00000032045	COP1 E3 ubiquitin ligase.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.978
DET1	COP1	ENSCATP00000034514	ENSCATP00000006359	Uncharacterized protein.	COP1 E3 ubiquitin ligase.	0.987
DET1	ETV1	ENSCATP00000034514	ENSCATP00000001005	Uncharacterized protein.	ETS variant 1.	0.819
DET1	ETV5	ENSCATP00000034514	ENSCATP00000038587	Uncharacterized protein.	ETS variant 5.	0.818
DET1	STK40	ENSCATP00000034514	ENSCATP00000032869	Uncharacterized protein.	Serine/threonine kinase 40.	0.811
EP300	ETV1	ENSCATP00000042119	ENSCATP00000001005	E1A binding protein p300.	ETS variant 1.	0.652
EP300	EWSR1	ENSCATP00000042119	ENSCATP00000029144	E1A binding protein p300.	EWS RNA binding protein 1.	0.752
EP300	TP53	ENSCATP00000042119	ENSCATP00000032045	E1A binding protein p300.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.997
ETV1	COP1	ENSCATP00000001005	ENSCATP00000006359	ETS variant 1.	COP1 E3 ubiquitin ligase.	0.906
ETV1	DET1	ENSCATP00000001005	ENSCATP00000034514	ETS variant 1.	Uncharacterized protein.	0.819
ETV1	EP300	ENSCATP00000001005	ENSCATP00000042119	ETS variant 1.	E1A binding protein p300.	0.652
ETV1	ETV5	ENSCATP00000001005	ENSCATP00000038587	ETS variant 1.	ETS variant 5.	0.684
ETV1	EWSR1	ENSCATP00000001005	ENSCATP00000029144	ETS variant 1.	EWS RNA binding protein 1.	0.583
ETV1	KCNN2	ENSCATP00000001005	ENSCATP00000011601	ETS variant 1.	Potassium calcium-activated channel subfamily N member 2.	0.569
ETV1	KCNN3	ENSCATP00000001005	ENSCATP00000026158	ETS variant 1.	Potassium calcium-activated channel subfamily N member 3.	0.569
ETV1	STK40	ENSCATP00000001005	ENSCATP00000032869	ETS variant 1.	Serine/threonine kinase 40.	0.900