Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SOCS3Suppressor of cytokine signaling 3. (225 aa)    
Predicted Functional Partners:
JAK2
Tyrosine-protein kinase.
   
 0.998
JAK1
Tyrosine-protein kinase.
   
 0.993
JAK3
Tyrosine-protein kinase.
   
 0.992
TYK2
Tyrosine-protein kinase.
   
 0.990
STAT3
Signal transducer and activator of transcription.
   
 0.989
STAT1
Signal transducer and activator of transcription.
   
 0.989
SOCS1
Suppressor of cytokine signaling 1.
   
 
0.987
IRS1
Insulin receptor substrate 1.
    
 0.984
LEPR
Leptin receptor.
    
 0.982
STAT2
Signal transducer and activator of transcription.
   
 0.981
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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