Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NLRP11NLR family pyrin domain containing 11. (1034 aa)    
Predicted Functional Partners:
MYO10
Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
   0.647
IFI16
Interferon gamma inducible protein 16.
  
   
 0.622
MAVS
Mitochondrial antiviral signaling protein.
  
 
 
 0.520
RNASEL
Ribonuclease L.
    
 0.457
MEFV
MEFV innate immuity regulator, pyrin.
      
 0.448
PGLYRP1
Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity.
      
 0.437
FAM47A
Family with sequence similarity 47 member A.
  
 
   0.434
PYHIN1
Pyrin and HIN domain family member 1.
  
   
 0.409
FAM47B
Family with sequence similarity 47 member B.
  
 
   0.402
CST9
Uncharacterized protein.
  
  
  0.400
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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