Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PROX2Prospero homeobox 2. (592 aa)    
Predicted Functional Partners:
IFT80
Intraflagellar transport 80.
      
 0.709
CATSPER1
Cation channel sperm associated 1.
      
 0.687
IGSF5
Immunoglobulin superfamily member 5.
      
 0.608
ZFYVE26
Zinc finger FYVE-type containing 26.
      
 0.598
TMEM236
Transmembrane protein 236.
      
 0.598
PRPF6
Pre-mRNA processing factor 6.
      
 0.596
VRTN
Vertebrae development associated.
      
 0.583
HDAC3
Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    
   0.582
TXLNB
Taxilin beta.
      
 0.516
FLRT2
Fibronectin leucine rich transmembrane protein 2.
      
 0.506
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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