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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)    
Predicted Functional Partners:
TNFRSF1A
TNF receptor superfamily member 1A.
    
 0.997
TNFRSF1B
TNF receptor superfamily member 1B.
   
 0.997
TNFAIP3
TNF alpha induced protein 3.
   
 0.981
TRADD
TNFRSF1A associated via death domain.
    
 0.978
RIPK1
Receptor interacting serine/threonine kinase 1.
   
 0.977
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
   
 0.975
IKBKG
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.
    
 0.974
TRAF2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.973
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
   
 0.970
TBK1
TANK binding kinase 1.
   
 0.968
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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