Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PREX2Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2. (1606 aa)    
Predicted Functional Partners:
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
    
 0.853
RAC3
Rac family small GTPase 3.
    
 0.791
RAC1
Uncharacterized protein.
    
 0.791
RAC2
Rac family small GTPase 2.
    
 0.791
LOC105571533
Uncharacterized protein.
    
 0.760
VAPB
VAMP associated protein B and C.
    
   0.726
RHOG
Uncharacterized protein.
    
 0.700
ENSCATP00000011395
Uncharacterized protein.
    
 0.700
ITSN1
Intersectin 1.
    
 0.680
RHOQ
Ras homolog family member Q.
    
 0.672
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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