Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (288 aa)    
Predicted Functional Partners:
FGFR2
Fibroblast growth factor receptor.
   
 0.997
FGFR1
Fibroblast growth factor receptor.
   
 0.997
FGFR3
Fibroblast growth factor receptor.
   
 0.993
FGFR4
Fibroblast growth factor receptor.
   
 0.991
SDC1
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
    
 0.937
GPC1
Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
    
 0.925
RET
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
    
 0.908
PTX3
Pentraxin 3.
    
 
 0.907
KDR
Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
 0.878
SDC4
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
    
 0.867
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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