Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PCDH17Protocadherin 17. (1187 aa)    
Predicted Functional Partners:
LOC105592899
Uncharacterized protein.
    
   0.864
PCDH12
Protocadherin 12.
   
 
 0.784
KCNS3
Potassium voltage-gated channel modifier subfamily S member 3; Belongs to the potassium channel family.
   
  
 0.697
KCNG3
Potassium voltage-gated channel modifier subfamily G member 3; Belongs to the potassium channel family.
      
 0.570
OLFM4
Olfactomedin 4.
      
 0.563
LRRTM1
Leucine rich repeat transmembrane neuronal 1.
     
 0.502
GRM2
Glutamate metabotropic receptor 2.
      
 0.501
COQ6
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
      
 0.472
KCTD1
BTB domain-containing protein.
      
 0.468
FNTB
Protein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.
      
 0.458
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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