Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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TRHDEThyrotropin releasing hormone degrading enzyme. (1067 aa)    
Predicted Functional Partners:
TRH
Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
      
 0.648
AGT
Angiotensinogen; Belongs to the serpin family.
   
 0.627
GSR
Glutathione-disulfide reductase.
   
 0.455
NR3C1
Nuclear receptor subfamily 3 group C member 1.
      
 0.451
PRLR
Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin.
      
 0.448
DLD
Dihydrolipoyl dehydrogenase.
   
 0.437
CAMKMT
Calmodulin-lysine N-methyltransferase.
    
 
 0.435
THRB
Thyroid hormone receptor beta.
      
 0.427
CLN5
Uncharacterized protein.
      
 0.425
HTR1E
5-hydroxytryptamine receptor 1E.
     
 0.423
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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