Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ZNF668Zinc finger protein 668. (619 aa)    
Predicted Functional Partners:
NOL12
Uncharacterized protein.
    
   0.823
GPATCH4
G-patch domain containing 4.
    
   0.749
KAT8
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
    
 
 0.706
RRP8
Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...]
   
   0.655
ZNF512
Zinc finger protein 512.
    
  0.654
UBE3D
Ubiquitin protein ligase E3D.
      
 0.623
PPAN
Peter pan homolog.
   
   0.600
RPL10
Ribosomal_L16 domain-containing protein.
    
   0.595
GALNT7
Polypeptide N-acetylgalactosaminyltransferase.
      
 0.573
SEC23IP
SEC23 interacting protein.
      
 0.571
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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