Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PROCRProtein C receptor. (238 aa)    
Predicted Functional Partners:
PROC
Protein C, inactivator of coagulation factors Va and VIIIa.
    
 0.970
F2R
Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family.
    
 0.953
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
    
 0.868
F7
Coagulation factor VII.
    
 0.864
PROS1
Protein S.
     
 0.747
F10
Coagulation factor X.
    
 0.658
F9
Coagulation factor IX.
    
 0.634
CD177
CD177 molecule.
     
  0.604
PF4
C-X-C motif chemokine.
     
 0.593
PF4V1
C-X-C motif chemokine.
     
 0.585
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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