| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APAF1 | CASP9 | ENSCATP00000040795 | ENSCATP00000005591 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Caspase 9; Belongs to the peptidase C14A family. | 0.999 |
| APAF1 | CYC1 | ENSCATP00000040795 | ENSCATP00000040451 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Cytochrome c1. | 0.591 |
| APAF1 | LOC105595720 | ENSCATP00000040795 | ENSCATP00000001239 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.882 |
| APAF1 | UQCR10 | ENSCATP00000040795 | ENSCATP00000003511 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Ubiquinol-cytochrome c reductase, complex III subunit X. | 0.609 |
| APAF1 | UQCRFS1 | ENSCATP00000040795 | ENSCATP00000028250 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | 0.556 |
| CASP9 | APAF1 | ENSCATP00000005591 | ENSCATP00000040795 | Caspase 9; Belongs to the peptidase C14A family. | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | 0.999 |
| CASP9 | LOC105595720 | ENSCATP00000005591 | ENSCATP00000001239 | Caspase 9; Belongs to the peptidase C14A family. | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.857 |
| CYC1 | APAF1 | ENSCATP00000040451 | ENSCATP00000040795 | Cytochrome c1. | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | 0.591 |
| CYC1 | ENSCATP00000016901 | ENSCATP00000040451 | ENSCATP00000016901 | Cytochrome c1. | Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. | 0.999 |
| CYC1 | ENSCATP00000042511 | ENSCATP00000040451 | ENSCATP00000042511 | Cytochrome c1. | Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. | 0.996 |
| CYC1 | LOC105595720 | ENSCATP00000040451 | ENSCATP00000001239 | Cytochrome c1. | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.925 |
| CYC1 | UQCR10 | ENSCATP00000040451 | ENSCATP00000003511 | Cytochrome c1. | Ubiquinol-cytochrome c reductase, complex III subunit X. | 0.999 |
| CYC1 | UQCRB | ENSCATP00000040451 | ENSCATP00000017737 | Cytochrome c1. | Ubiquinol-cytochrome c reductase binding protein. | 0.999 |
| CYC1 | UQCRC2 | ENSCATP00000040451 | ENSCATP00000006891 | Cytochrome c1. | Ubiquinol-cytochrome c reductase core protein 2; Belongs to the peptidase M16 family. | 0.999 |
| CYC1 | UQCRFS1 | ENSCATP00000040451 | ENSCATP00000028250 | Cytochrome c1. | Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | 0.999 |
| CYC1 | UQCRQ | ENSCATP00000040451 | ENSCATP00000030914 | Cytochrome c1. | Ubiquinol-cytochrome c reductase complex III subunit VII. | 0.999 |
| ENSCATP00000016901 | CYC1 | ENSCATP00000016901 | ENSCATP00000040451 | Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. | Cytochrome c1. | 0.999 |
| ENSCATP00000016901 | LOC105595720 | ENSCATP00000016901 | ENSCATP00000001239 | Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.828 |
| ENSCATP00000016901 | UQCR10 | ENSCATP00000016901 | ENSCATP00000003511 | Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. | Ubiquinol-cytochrome c reductase, complex III subunit X. | 0.996 |
| ENSCATP00000016901 | UQCRC2 | ENSCATP00000016901 | ENSCATP00000006891 | Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. | Ubiquinol-cytochrome c reductase core protein 2; Belongs to the peptidase M16 family. | 0.999 |