Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
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textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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PTPN12Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. (780 aa)    
Predicted Functional Partners:
PSTPIP1
Proline-serine-threonine phosphatase interacting protein 1.
   
 
 0.960
EGFR
Receptor protein-tyrosine kinase.
    
 0.955
PXN
Paxillin.
   
 0.928
PSTPIP2
Proline-serine-threonine phosphatase interacting protein 2.
   
 
 0.918
BCAR1
BCAR1 scaffold protein, Cas family member.
    
 
 0.897
CSK
Tyrosine-protein kinase.
   
 0.896
ENSCATP00000007407
PID domain-containing protein.
    
 0.883
LOC105585293
Uncharacterized protein.
    
 0.883
SHC1
SHC adaptor protein 1.
    
 0.883
PDGFRB
Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.
    
 0.798
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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