Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISG15ISG15 ubiquitin like modifier. (165 aa)    
Predicted Functional Partners:
DDX58
DExD/H-box helicase 58.
   
 0.999
IRF3
Interferon regulatory factor 3.
   
 0.997
UBE2L6
Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.996
UBA7
Ubiquitin like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family.
   
 0.995
IFIH1
Interferon induced with helicase C domain 1.
   
 0.995
USP18
USP domain-containing protein; Belongs to the peptidase C19 family.
   
 0.988
HERC5
HECT and RLD domain containing E3 ubiquitin protein ligase 5.
   
 0.987
NEDD4
NEDD4 E3 ubiquitin protein ligase.
    
 0.979
EIF2AK2
Eukaryotic translation initiation factor 2 alpha kinase 2.
   
 
 0.978
UBA1
Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family.
   
 0.975
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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