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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISG15ISG15 ubiquitin like modifier. (165 aa)    
Predicted Functional Partners:
USP18
USP domain-containing protein; Belongs to the peptidase C19 family.
   
 0.991
DDX58
DExD/H-box helicase 58.
   
 0.989
MYSM1
Myb like, SWIRM and MPN domains 1.
    
 0.984
UBXN7
UBX domain-containing protein 7.
    
 0.983
UBA7
Ubiquitin like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family.
   
 0.971
FANCM
FA complementation group M.
   
 0.955
EIF2AK2
Eukaryotic translation initiation factor 2 alpha kinase 2.
   
 
 0.954
HERC5
HECT and RLD domain containing E3 ubiquitin protein ligase 5.
   
 0.953
IRF7
Interferon regulatory factor 7.
   
 
 0.951
MX1
MX dynamin like GTPase 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
   
 0.951
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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