Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSCATP00000001361DUF4203 domain-containing protein. (100 aa)    
Predicted Functional Partners:
APAF1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 0.707
BIRC6
Baculoviral IAP repeat containing 6.
   
 0.547
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
    
 0.466
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
    
 0.466
CENPN
Centromere protein N.
   
 0.434
MIB2
Mindbomb E3 ubiquitin protein ligase 2.
    
 0.410
CENPM
Centromere protein M.
   
 0.407
NAIP
NLR family apoptosis inhibitory protein.
   
 0.402
BIRC3
Baculoviral IAP repeat containing 3.
   
 0.402
XIAP
X-linked inhibitor of apoptosis.
   
 0.402
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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