Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ENSCATP00000001404Uncharacterized protein; Belongs to the LDH/MDH superfamily. (344 aa)    
Predicted Functional Partners:
GOT2
Aspartate aminotransferase.
   
 0.960
PC
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 0.959
PKM
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.958
PKLR
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.954
ME1
Malic enzyme.
  
 
 0.951
GOT1
Aspartate aminotransferase.
   
 0.950
ME3
Malic enzyme.
  
 
 0.950
GOT1L1
Glutamic-oxaloacetic transaminase 1 like 1.
   
 0.947
ME2
Malic enzyme.
  
 
 0.945
PDHB
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 0.939
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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