STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBFA2T2CBFA2/RUNX1 partner transcriptional co-repressor 2. (602 aa)    
Predicted Functional Partners:
PRDM14
PR/SET domain 14.
    
 
 0.956
PRDM6
PR/SET domain 6.
    
 
 0.906
CBFA2T3
CBFA2/RUNX1 partner transcriptional co-repressor 3.
   
 
 0.901
TFAP2C
Transcription factor AP-2 gamma.
     
 0.801
NUDCD1
NudC domain containing 1.
    
   0.777
SOX17
SRY-box transcription factor 17.
     
 0.746
RUNX1T1
RUNX1 partner transcriptional co-repressor 1.
   
   0.745
ENSCATP00000012642
Uncharacterized protein.
   
   0.745
ENSCATP00000020372
annotation not available
   
   0.745
RUNX1
Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
    
 
 0.740
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.