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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EXO1Exonuclease 1. (846 aa)    
Predicted Functional Partners:
WRN
WRN RecQ like helicase.
  
 0.998
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.994
MLH1
MutL homolog 1.
   
 0.993
MSH2
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
   
 0.993
BLM
BLM RecQ like helicase.
  
 0.992
RECQL4
RecQ like helicase 4.
  
 0.990
PMS2
PMS1 homolog 2, mismatch repair system component.
   
 0.988
RAD51
RAD51 recombinase; Belongs to the RecA family.
  
 0.988
DNA2
DNA replication helicase/nuclease 2.
   
 0.981
SLF1
SMC5-SMC6 complex localization factor 1.
   
 0.973
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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