Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EXO1Exonuclease 1. (846 aa)    
Predicted Functional Partners:
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.988
BLM
BLM RecQ like helicase.
  
 0.986
MSH2
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
   
 0.985
WRN
WRN RecQ like helicase.
  
 0.984
MLH1
MutL homolog 1.
   
 0.984
RAD51
RAD51 recombinase; Belongs to the RecA family.
  
 0.982
DNA2
DNA replication helicase/nuclease 2.
   
 0.979
RECQL4
RecQ like helicase 4.
  
 0.974
RBBP8
RB binding protein 8, endonuclease.
    
 0.967
LOC105599742
Zinc-hook domain-containing protein.
  
 0.962
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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