Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NAIPNLR family apoptosis inhibitory protein. (1403 aa)    
Predicted Functional Partners:
NLRC4
NLR family CARD domain containing 4.
  
0.991
CASP1
Caspase 1; Belongs to the peptidase C14A family.
   
 0.944
XIAP
X-linked inhibitor of apoptosis.
   
 0.910
CASP9
Caspase 9; Belongs to the peptidase C14A family.
   
 0.904
DIABLO
Uncharacterized protein.
    
 0.883
PYCARD
PYD and CARD domain containing.
    
 0.878
TNFRSF1A
TNF receptor superfamily member 1A.
    
 0.841
TRADD
TNFRSF1A associated via death domain.
   
 0.834
CASP12
Caspase 12 (gene/pseudogene); Belongs to the peptidase C14A family.
   
 0.823
LOC105588756
Caspase recruitment domain family member 17.
   
 0.823
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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