| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APAF1 | BAX | ENSCATP00000040795 | ENSCATP00000004246 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | BCL2 associated X, apoptosis regulator. | 0.759 |
| APAF1 | BCL2 | ENSCATP00000040795 | ENSCATP00000042993 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | BCL2 apoptosis regulator. | 0.842 |
| APAF1 | BCL2L1 | ENSCATP00000040795 | ENSCATP00000021428 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | BCL2 like 1. | 0.827 |
| APAF1 | CASP3 | ENSCATP00000040795 | ENSCATP00000010319 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Uncharacterized protein; Belongs to the peptidase C14A family. | 0.979 |
| APAF1 | CASP9 | ENSCATP00000040795 | ENSCATP00000005591 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Caspase 9; Belongs to the peptidase C14A family. | 0.999 |
| APAF1 | CYC1 | ENSCATP00000040795 | ENSCATP00000040451 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Cytochrome c1. | 0.686 |
| APAF1 | ENSCATP00000001452 | ENSCATP00000040795 | ENSCATP00000001452 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.987 |
| APAF1 | ENSCATP00000038453 | ENSCATP00000040795 | ENSCATP00000038453 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Uncharacterized protein; Belongs to the peptidase C14A family. | 0.976 |
| BAX | APAF1 | ENSCATP00000004246 | ENSCATP00000040795 | BCL2 associated X, apoptosis regulator. | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | 0.759 |
| BAX | BCL2 | ENSCATP00000004246 | ENSCATP00000042993 | BCL2 associated X, apoptosis regulator. | BCL2 apoptosis regulator. | 0.998 |
| BAX | BCL2L1 | ENSCATP00000004246 | ENSCATP00000021428 | BCL2 associated X, apoptosis regulator. | BCL2 like 1. | 0.997 |
| BAX | CASP3 | ENSCATP00000004246 | ENSCATP00000010319 | BCL2 associated X, apoptosis regulator. | Uncharacterized protein; Belongs to the peptidase C14A family. | 0.422 |
| BAX | CASP9 | ENSCATP00000004246 | ENSCATP00000005591 | BCL2 associated X, apoptosis regulator. | Caspase 9; Belongs to the peptidase C14A family. | 0.401 |
| BAX | ENSCATP00000001452 | ENSCATP00000004246 | ENSCATP00000001452 | BCL2 associated X, apoptosis regulator. | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.893 |
| BAX | ENSCATP00000038453 | ENSCATP00000004246 | ENSCATP00000038453 | BCL2 associated X, apoptosis regulator. | Uncharacterized protein; Belongs to the peptidase C14A family. | 0.422 |
| BCL2 | APAF1 | ENSCATP00000042993 | ENSCATP00000040795 | BCL2 apoptosis regulator. | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | 0.842 |
| BCL2 | BAX | ENSCATP00000042993 | ENSCATP00000004246 | BCL2 apoptosis regulator. | BCL2 associated X, apoptosis regulator. | 0.998 |
| BCL2 | BCL2L1 | ENSCATP00000042993 | ENSCATP00000021428 | BCL2 apoptosis regulator. | BCL2 like 1. | 0.989 |
| BCL2 | CASP3 | ENSCATP00000042993 | ENSCATP00000010319 | BCL2 apoptosis regulator. | Uncharacterized protein; Belongs to the peptidase C14A family. | 0.696 |
| BCL2 | CASP9 | ENSCATP00000042993 | ENSCATP00000005591 | BCL2 apoptosis regulator. | Caspase 9; Belongs to the peptidase C14A family. | 0.741 |