Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CNR2Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. (360 aa)    
Predicted Functional Partners:
ARRB1
Arrestin beta 1.
    
 0.762
ADORA2A
Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.
    
 
 0.760
GPR18
G protein-coupled receptor 18; Belongs to the G-protein coupled receptor 1 family.
    
 0.739
GNAI2
G protein subunit alpha i2.
    
  0.731
GNAI3
G protein subunit alpha i3.
    
  0.636
GNAI1
G protein subunit alpha i1.
    
  0.636
ADORA2B
Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.
    
   0.632
LPAR4
Lysophosphatidic acid receptor 4; Belongs to the G-protein coupled receptor 1 family.
     
 0.620
GNG2
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
  0.610
GNB4
G protein subunit beta 4.
    
  0.605
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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