Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CGASCyclic GMP-AMP synthase. (522 aa)    
Predicted Functional Partners:
H2BC21
Histone H2B; Belongs to the histone H2B family.
    
 
 0.789
H2AC20
Histone H2A; Belongs to the histone H2A family.
    
 
 0.785
H2BC5
Histone H2B; Belongs to the histone H2B family.
    
 
 0.780
H2AC6
Histone H2A; Belongs to the histone H2A family.
    
   0.776
H2AJ
Histone H2A; Belongs to the histone H2A family.
    
 
 0.776
SPSB3
SplA/ryanodine receptor domain and SOCS box containing 3.
    
   0.776
LOC105593167
Histone H2B; Belongs to the histone H2B family.
    
   0.776
H2AC21
Histone H2A; Belongs to the histone H2A family.
    
   0.776
IRF3
Interferon regulatory factor 3.
      
 0.764
STING1
Transmembrane protein 173.
    
 0.763
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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