STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CGASCyclic GMP-AMP synthase. (522 aa)    
Predicted Functional Partners:
H2AC20
Histone H2A; Belongs to the histone H2A family.
    
 
 0.834
IFI16
Interferon gamma inducible protein 16.
    
 
 0.813
STING1
Transmembrane protein 173.
    
 0.794
IRF3
Interferon regulatory factor 3.
      
 0.710
LOC105572669
Histone H2A; Belongs to the histone H2A family.
    
   0.704
H2AC4
Histone H2A type 1.
    
   0.704
H2BC11
Histone H2B; Belongs to the histone H2B family.
    
   0.696
TLR7
Toll-like receptor 7; Belongs to the Toll-like receptor family.
      
 0.696
TBK1
TANK binding kinase 1.
      
 0.671
DDX41
DEAD-box helicase 41.
      
 0.669
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.