FAF1 protein (Cercocebus atys) - STRING interaction network

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Known Interactions

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Predicted Interactions

gene neighborhood

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textmining

co-expression

protein homology

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[Homology]

Score

FAF1

Fas associated factor 1. (651 aa)

Predicted Functional Partners:

VCP

0.987

UBXN1

0.985

UBXN7

0.971

UBXN6

0.969

NPLOC4

0.964

ASPSCR1

0.958

UBXN2B

0.953

FADD

0.939

FAS

0.930

TNFAIP1

0.926

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASPSCR1	FAF1	ENSCATP00000034012	ENSCATP00000001549	ASPSCR1 tether for SLC2A4, UBX domain containing.	Fas associated factor 1.	0.958
ASPSCR1	NPLOC4	ENSCATP00000034012	ENSCATP00000026383	ASPSCR1 tether for SLC2A4, UBX domain containing.	NPL4 homolog, ubiquitin recognition factor.	0.948
ASPSCR1	UBXN1	ENSCATP00000034012	ENSCATP00000026622	ASPSCR1 tether for SLC2A4, UBX domain containing.	UBX domain protein 1.	0.807
ASPSCR1	UBXN2B	ENSCATP00000034012	ENSCATP00000026301	ASPSCR1 tether for SLC2A4, UBX domain containing.	UBX domain protein 2B.	0.960
ASPSCR1	UBXN6	ENSCATP00000034012	ENSCATP00000032554	ASPSCR1 tether for SLC2A4, UBX domain containing.	UBX domain protein 6.	0.946
ASPSCR1	UBXN7	ENSCATP00000034012	ENSCATP00000006661	ASPSCR1 tether for SLC2A4, UBX domain containing.	UBX domain-containing protein 7.	0.986
ASPSCR1	VCP	ENSCATP00000034012	ENSCATP00000008392	ASPSCR1 tether for SLC2A4, UBX domain containing.	Valosin containing protein; Belongs to the AAA ATPase family.	0.960
FADD	FAF1	ENSCATP00000024261	ENSCATP00000001549	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Fas associated factor 1.	0.939
FADD	FAS	ENSCATP00000024261	ENSCATP00000040382	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Tumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen- stimulated suicide of mature T-cells, or both (By similarity).	0.996
FAF1	ASPSCR1	ENSCATP00000001549	ENSCATP00000034012	Fas associated factor 1.	ASPSCR1 tether for SLC2A4, UBX domain containing.	0.958
FAF1	FADD	ENSCATP00000001549	ENSCATP00000024261	Fas associated factor 1.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.939
FAF1	FAS	ENSCATP00000001549	ENSCATP00000040382	Fas associated factor 1.	Tumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen- stimulated suicide of mature T-cells, or both (By similarity).	0.930
FAF1	NPLOC4	ENSCATP00000001549	ENSCATP00000026383	Fas associated factor 1.	NPL4 homolog, ubiquitin recognition factor.	0.964
FAF1	TNFAIP1	ENSCATP00000001549	ENSCATP00000026583	Fas associated factor 1.	TNF alpha induced protein 1.	0.926
FAF1	UBXN1	ENSCATP00000001549	ENSCATP00000026622	Fas associated factor 1.	UBX domain protein 1.	0.985
FAF1	UBXN2B	ENSCATP00000001549	ENSCATP00000026301	Fas associated factor 1.	UBX domain protein 2B.	0.953
FAF1	UBXN6	ENSCATP00000001549	ENSCATP00000032554	Fas associated factor 1.	UBX domain protein 6.	0.969
FAF1	UBXN7	ENSCATP00000001549	ENSCATP00000006661	Fas associated factor 1.	UBX domain-containing protein 7.	0.971
FAF1	VCP	ENSCATP00000001549	ENSCATP00000008392	Fas associated factor 1.	Valosin containing protein; Belongs to the AAA ATPase family.	0.987
FAS	FADD	ENSCATP00000040382	ENSCATP00000024261	Tumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen- stimulated suicide of mature T-cells, or both (By similarity).	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.996