Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAK5Non-specific serine/threonine protein kinase. (719 aa)    
Predicted Functional Partners:
LOC105571986
Uncharacterized protein.
   
 0.973
ENSCATP00000004469
Uncharacterized protein.
   
 0.973
NCK1
Cytoplasmic protein.
    
 0.966
NCK2
Cytoplasmic protein.
    
 0.966
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
    
 0.957
ARHGEF7
Rho guanine nucleotide exchange factor 7.
    
 0.957
RAC3
Rac family small GTPase 3.
   
 0.955
RAC1
Uncharacterized protein.
   
 0.955
RAC2
Rac family small GTPase 2.
   
 0.955
PAK6
Non-specific serine/threonine protein kinase.
   
 0.952
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
Server load: low (16%) [HD]