STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HPSEHeparanase. (539 aa)    
Predicted Functional Partners:
SDC1
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
     
 0.994
HPSE2
Heparanase 2 (inactive).
  
  
0.959
IDS
Sulfatase domain-containing protein.
     
  0.900
SDC3
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
     
 0.667
CTSL
Cathepsin L; Belongs to the peptidase C1 family.
   
 
 0.625
NR2C2
Nuclear receptor subfamily 2 group C member 2.
    
   0.611
CTSV
Cathepsin V; Belongs to the peptidase C1 family.
   
 
 0.607
GPC1
Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
     
 0.606
SDC4
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
     
 0.579
GPC3
Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
     
 0.570
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.