Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSCATP00000001613Ras-GEF domain-containing protein. (602 aa)    
Predicted Functional Partners:
HRAS
HRas proto-oncogene, GTPase.
    
 0.942
RALA
RAS like proto-oncogene A.
    
 0.934
RALB
RAS like proto-oncogene B.
    
 0.926
KRAS
KRAS proto-oncogene, GTPase.
    
 0.919
NRAS
NRAS proto-oncogene, GTPase.
    
 0.919
RRAS
RAS related.
    
  0.917
RRAS2
RAS related 2.
    
  0.917
MRAS
Muscle RAS oncogene homolog.
    
  0.917
RAP1B
Uncharacterized protein.
    
  0.917
RAP1A
RAP1A, member of RAS oncogene family.
    
  0.917
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.