Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SMC6Structural maintenance of chromosomes 6. (1092 aa)    
Predicted Functional Partners:
SMC5
SMC_N domain-containing protein.
   
0.997
NSMCE1
NSE1 homolog, SMC5-SMC6 complex component.
    
 0.995
NSMCE4A
Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
   
 0.995
ENSCATP00000020360
SP-RING-type domain-containing protein.
    
 0.985
NSMCE2
SP-RING-type domain-containing protein.
    
 0.985
SMC3
Structural maintenance of chromosomes 3.
   
 0.942
MAGEF1
MAGE family member F1.
   
 0.911
MAGEE1
MAGE family member E1.
   
 0.911
ZNF597
Zinc finger protein 597.
    
   0.900
RAD51
RAD51 recombinase; Belongs to the RecA family.
    
 
 0.856
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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