CXCL12 protein (Cercocebus atys) - STRING interaction network

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Score

CXCL12

C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa)

Predicted Functional Partners:

CXCR4

0.999

ACKR3

0.996

CCL21

0.973

CXCL11

0.967

CXCL9

0.967

CXCL10

0.966

CCL5

0.965

PF4

0.957

PPBP

0.957

CCL25

0.955

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACKR3	CCL25	ENSCATP00000007177	ENSCATP00000031814	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine ligand 25.	0.413
ACKR3	CXCL10	ENSCATP00000007177	ENSCATP00000024629	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine.	0.482
ACKR3	CXCL11	ENSCATP00000007177	ENSCATP00000020934	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine.	0.845
ACKR3	CXCL12	ENSCATP00000007177	ENSCATP00000001623	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.	0.996
ACKR3	CXCL9	ENSCATP00000007177	ENSCATP00000031416	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine ligand 9.	0.533
ACKR3	CXCR4	ENSCATP00000007177	ENSCATP00000002499	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade (By similarity). Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS- induced inflammatory response, including TNF secretion by monocytes (By similarity). Inv [...]	0.993
CCL21	CCL25	ENSCATP00000040238	ENSCATP00000031814	C-C motif chemokine ligand 21.	C-C motif chemokine ligand 25.	0.669
CCL21	CCL5	ENSCATP00000040238	ENSCATP00000040226	C-C motif chemokine ligand 21.	C-C motif chemokine.	0.955
CCL21	CXCL10	ENSCATP00000040238	ENSCATP00000024629	C-C motif chemokine ligand 21.	C-X-C motif chemokine.	0.960
CCL21	CXCL11	ENSCATP00000040238	ENSCATP00000020934	C-C motif chemokine ligand 21.	C-X-C motif chemokine.	0.959
CCL21	CXCL12	ENSCATP00000040238	ENSCATP00000001623	C-C motif chemokine ligand 21.	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.	0.973
CCL21	CXCL9	ENSCATP00000040238	ENSCATP00000031416	C-C motif chemokine ligand 21.	C-X-C motif chemokine ligand 9.	0.961
CCL21	CXCR4	ENSCATP00000040238	ENSCATP00000002499	C-C motif chemokine ligand 21.	C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade (By similarity). Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS- induced inflammatory response, including TNF secretion by monocytes (By similarity). Inv [...]	0.845
CCL21	PF4	ENSCATP00000040238	ENSCATP00000024123	C-C motif chemokine ligand 21.	C-X-C motif chemokine.	0.930
CCL21	PPBP	ENSCATP00000040238	ENSCATP00000024226	C-C motif chemokine ligand 21.	C-X-C motif chemokine.	0.925
CCL25	ACKR3	ENSCATP00000031814	ENSCATP00000007177	C-C motif chemokine ligand 25.	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.413
CCL25	CCL21	ENSCATP00000031814	ENSCATP00000040238	C-C motif chemokine ligand 25.	C-C motif chemokine ligand 21.	0.669
CCL25	CCL5	ENSCATP00000031814	ENSCATP00000040226	C-C motif chemokine ligand 25.	C-C motif chemokine.	0.955
CCL25	CXCL10	ENSCATP00000031814	ENSCATP00000024629	C-C motif chemokine ligand 25.	C-X-C motif chemokine.	0.785
CCL25	CXCL11	ENSCATP00000031814	ENSCATP00000020934	C-C motif chemokine ligand 25.	C-X-C motif chemokine.	0.951