STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TOX4TOX high mobility group box family member 4. (621 aa)    
Predicted Functional Partners:
WDR82
WD repeat domain 82.
    
 0.744
PPP1R10
Protein phosphatase 1 regulatory subunit 10.
   
 0.662
PPP1CA
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
  0.634
PPP1CB
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
  0.611
ACTR8
Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.
    
 0.580
RUVBL1
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.
    
 0.554
ERCC3
ERCC excision repair 3, TFIIH core complex helicase subunit.
   
 0.545
GTF2H3
General transcription factor IIH subunit 3.
    
 0.543
PPP1CC
Serine/threonine-protein phosphatase.
   
  0.530
POLRMT
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family.
    
 0.525
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.