STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
L3MBTL3L3MBTL histone methyl-lysine binding protein 3. (780 aa)    
Predicted Functional Partners:
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
   
 
 0.775
TP53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
   
 0.630
EED
Embryonic ectoderm development.
   
 0.575
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
    
 
 0.563
SMG5
SMG5 nonsense mediated mRNA decay factor.
      
 0.557
YAF2
YY1 associated factor 2.
    
 0.487
RYBP
RING1 and YY1 binding protein.
    
 0.487
SMG6
SMG6 nonsense mediated mRNA decay factor.
      
 0.485
CBX8
Chromobox 8.
    
 0.458
RNF2
Ring finger protein 2.
    
 0.448
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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